Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep959 | Steroid metabolism + action | ECE2016

Effect of estradiol on the development of hypoxic pulmonary hypertension (O2=13%, 10%, 6%) and blood hematocrit in the female ovariectomized rats

Medvedeva Natalia , Medvedev Oleg

Objective: The role of sex in pulmonary hypertension (PAH) is not fully known. The majority of animal studies have suggested a protective role of female sex hormone in PAH. But women of various ages are more subjected to PAH compared with male. The aim of current research was to test the hypothesis that the level of oxygen in the inspired air can influence on the effect of estradiol on the development of experimental PAH in female rats.Methods and design...